Table 2.
Inhibition constants of acetyl/malonyl-oxa/aza(dethia)CoA analogs.
| Substrate or Product analog | Ki (mM) |
|---|---|
| 1 acetyl-oxa(dethia)CoA | weak activation |
| 2 acetyl-aza(dethia)CoA | 0.8±0.1 |
| 3 malonyl-oxa(dethia)CoA | 0.8±0.4 |
| 4 malonyl-aza(dethia)CoA | 0.7±0.3 |
| 5 oxa(dethia)CoA | 0.4±0.2 |
| 6 aza(dethia)CoA | 0.9±0.4 |
| CoA | 0.15±0.07 |