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. 2023 Jun 16;14:1190883. doi: 10.3389/fimmu.2023.1190883

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Copyright © 2023 Ai, Yang, Li, Ma, Liu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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There are many detours and challenges in the CTA-based digestive tract tumor immunotherapy. New strategies and cutting-edge technology provided opportunities to overcome these difficulties.