Table 12.2.

Select drug screening experiments in tumor slice culture models

Cancer type	Tumor source	Drugs tested	Reference
Pancreatic ductal adenocarcinoma	Patient	Staurosporine, cycloheximide	[89]
Pancreatic ductal adenocarcinoma	Patient	Rapamycin	[90]
Colon, triple-negative breast cancer	PDX PDX	Staurosporine Panels of FDA-approved drugs	[91]
Colorectal cancer	Patient	Cetuximab, oxaliplatin, and pembrolizumab	[88]
Colorectal cancer	Patient	5-fluorouracil (5-FU) and FOLFOX (5-FU and oxaliplatin)	[92]
Breast	Patient	FAC (5-FU, doxorubicin, 4-HC or preactivated cyclophosphamide)	[93]
Glioma	Mouse	Cisplatin, temozolomide, paclitaxel, tranilast	[84]
Colon, lung, prostate	Human	LY294002 (PI3K inhibitor), Nutlin-3	[86]