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. Author manuscript; available in PMC: 2023 Jun 30.
Published in final edited form as: Life Sci. 2022 Sep 11;309:120952. doi: 10.1016/j.lfs.2022.120952

Figure 1: Expression of Cre recombinase in luteinizing hormone expressing cells in the pituitary and, unexpectedly, in the β-, α-, and δ-cells of pancreatic islets.

Figure 1:

(A) Representative immunofluorescence images of pituitary sections and (B) islets of Langerhans from αGSU-Cre+;Sun1-GFP reporter mice indicating active Cre recombination in co-immunolabeled cell types. Perinuclear GFP localization of Sun1-GFP is detectable in αGSU-Cre+ mice, but not Cre- mice. (C) Islets stained for insulin (n=53), glucagon (n=26), and somatostatin (n=27) were quantified for GFP and hormone colocalization as a percentage of total GFP+ cells of each cell type.