Table 1:
Trial Inclusion and Exclusion Criteria
| Inclusion |
|---|
| Be age 65 or older at time of consent |
| Have the ability to speak and understand English or Spanish |
| Report adequate sensorimotor capacity to perform the computer exercises |
| Report adequate visual capacity to read from a computer screen at a typical viewing distance |
| Show adequate auditory capacity to understand conversational speech |
| Show adequate motor capacity to touch a computer screen or control a computer mouse |
| Have no evidence of mild cognitive impairment (MCI) or dementia at baseline, as assessed by education adjusted Montreal Cognitive Assessment score >=26 |
| Have adequate mental health (no self-reported diagnosis or mental illness that would interfere with ability to comply with study procedures or benefit from intervention) |
| Wiling to complete all study activities |
| Ability to understand study procedures and comply with them for the length of the study |
| Exclusion |
| Currently enrolled in another randomized clinical trial, or treatment trial, or another research study that assesses cognition |
| Previous participation in a cognitive training study |
| Self-reported vision, hearing, or motor difficulties that would interfere with the ability to complete the study interventions |
| Self-reported diagnosis of mild cognitive impairment, dementia, stroke, traumatic brain injury, brain tumor, or a neurological disorder that affects cognition or would interfere with the ability to benefit from the study intervention (e.g., Parkinson disease, multiple sclerosis), or any other unstable medical condition that is predisposing to imminent cognitive or functional decline (e.g., congestive heart failure, chronic obstructive pulmonary disorder dependent on oxygen, or undergoing chemotherapy or radiation) |
| Self-reported use of medications typically prescribed for dementia such as Namenda, Memantine, Namzaric, Donepezil, Aricept, Rivastigmine, Exelon, Razadyne, Galantamine, Reminyl, Aduhelm or Aducanumab. |
| Completion of 10 or more hours of a computerized cognitive training program in the last 5 years such as Lumosity, Posit Science Brain Fitness, InSight or Brain HQ, Listening and Communication Enhancement (LACE), CogMed, CogniFit, Happy Neuron, Elevate, or Dakim |
| Severe depressive symptoms (GDS short form score >=5) |