Table 1.

Ranked changes of q_yr for the 35 cortical areas studied and the whole cortical gray matter

Rank	Area	Lobe	qyr (%) Linear	P Value Linear	r2(q) Linear Fit	r2(q′) Log Fit
1	Superior parietal	Parietal	−1.706	<0.001	0.446	0.461
2	Precuneus	Parietal	−1.532	<0.001	0.458	0.474
3	Inferior parietal	Parietal	−1.485	<0.001	0.337	0.336
4	Supramarginal	Parietal	−1.474	<0.001	0.306	0.309
5	Frontal pole	Frontal	−1.412	<0.001	0.225	0.231
6	Rostral middle frontal	Frontal	−1.389	<0.001	0.334	0.332
7	Postcentral	Parietal	−1.376	<0.001	0.324	0.340
8	Banks of superior temporal sulcus	Temporal	−1.297	<0.001	0.206	0.211
9	Caudal middle frontal	Frontal	−1.269	<0.001	0.189	0.187
10	Inferior frontal pars orbitalis	Frontal	−1.238	<0.001	0.266	0.266
11	Paracentral	Frontal	−1.230	<0.001	0.277	0.289
12	Superior frontal	Frontal	−1.196	<0.001	0.344	0.337
13	Inferior frontal pars triangularis	Frontal	−1.184	<0.001	0.180	0.185
14	Middle temporal	Temporal	−1.155	<0.001	0.281	0.274
15	Isthmus cingulate	Cingulate	−1.154	<0.001	0.188	0.197
16	Posterior cingulate	Cingulate	−1.115	<0.001	0.188	0.193
17	Lateral orbitofrontal	Frontal	−1.109	<0.001	0.316	0.323
18	Medial orbitofrontal	Frontal	−1.088	<0.001	0.174	0.182
19	Inferior frontal pars opercularis	Frontal	−1.057	<0.001	0.127	0.130
20	Transverse temporal	Temporal	−1.043	<0.001	0.114	0.123
21	Superior temporal	Temporal	−1.019	<0.001	0.250	0.254
22	Lateral occipital	Occipital	−0.974	<0.001	0.160	0.172
23	Inferior temporal	Temporal	−0.870	<0.001	0.146	0.134
24	Cuneus	Occipital	−0.826	<0.001	0.068	0.078
25	Precentral	Frontal	−0.794	<0.001	0.177	0.181
26	Caudal anterior cingulate	Cingulate	−0.781	<0.001	0.038	0.036
27	Fusiform	Temporal	−0.644	<0.001	0.103	0.109
28	Lingual	Occipital	−0.641	<0.001	0.047	0.052
29	Rostral anterior cingulate	Cingulate	−0.607	<0.001	0.032	0.033
30	Insula	Parietal	−0.257	<0.001	0.021	0.022
31	Parahippocampal	Temporal	−0.128	NS	0.002	0.003
32	Hippocampus	Temporal	−0.017	NS	0.000	0.000
33	Pericalcarine	Occipital	0.164	NS	0.001	0.000
34	Entorhinal	Temporal	0.254	NS	0.003	0.003
35	Temporal pole	Temporal	0.324	0.005	0.012	0.010
All cortical gray matter			−1.129	<0.001	0.562	0.571

The P values are from the regression analysis of q vs. years (Eq. 2) performed for each area (n = 649 per regression). r²(q) and r²(q′) are coefficients of determination from the q (Eq. 2) and q′ (Eq. 6) regressions, respectively. NS, not significant; q_yr, estimated percent change of q per year.