Figure 1 |. Variant-aware transcript detection by FLAIR2 identifies haplotype-specific transcript isoform bias.

a, FLAIR2 computational workflow for identifying haplotype-specific transcripts in long reads. b, FLAIR transcript models for MCM5 with the highest expression are plotted using different colors for each transcript’s exons. The highlighted portion shows alternative splicing and the smaller blocks within exons indicate variants. c, Stacked bar chart showing the proportion of transcript expression of transcripts from b as matched by color for each of the replicates sequenced.