Figure 3: Gene-level biological pathway annotation and tissue-specific gene expression.

a) Validation of the nine BAGs in gene set enrichment analyses. Gene set enrichment analyses were performed using curated gene sets and GO terms from the MsigDB database. b) Validation of the nine BAGs in gene-property analyses. Gene-property analyses evaluate tissue-specific gene expressions for the nine BAG-related genes using the full SNP P-values distribution. Only significant gene sets are presented after adjusting for multiple comparisons using the Bonferroni correction. Abbreviation: EGJ: esophagus gastroesophageal junction.