TABLE 2.

Outcomes of Patients With Loculated Nondraining Indwelling Pleural Catheters

	tPA	tPA+DNase	Procedural Intervention	No Therapy
Total	24	46	4	7
Improved drainage*
n (%)	20 (83)	35 (80)	3 (75)	0 (0)
OR (95% CI)	Reference	0.82 (0.23-2.92)	0.51 (0.05-5.53)	0.02 (<0.001-0.37)
Repeat procedure†
n (%)	4 (17)	12 (26)	2 (50)	3 (43)
HR (95% CI)	Reference	1.54 (0.48-4.89)	3.90 (0.65-23.58)	2.80 (0.63-12.35)
Autopleurodesis
n (%)	11 (46)	9 (20)	1 (25)	0 (0)
HR (95% CI)	Reference	0.36 (0.15-0.84)	0.48 (0.06-3.79)	0
Any complication
n (%)	4 (17)	10 (22)	0 (0)	0 (0)
HR (95% CI)	Reference	1.30 (0.41-4.16)	0	0

^*Unavailable outcome data for 2 patients.

^†Procedures included thoracentesis, chest tube/indwelling pleural catheter insertion, or thoracic surgery.

CI indicates confidence interval; DNase, deoxyribonuclease; HR, hazard ratio; OR, odds ratio; tPA, tissue plasminogen activator.