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[Preprint]. 2023 Jun 16:rs.3.rs-3026818. [Version 1] doi: 10.21203/rs.3.rs-3026818/v1

Extended Data Fig. 5. AlphaFold Multimer prediction of CCDC22-CCDC93 binding to Retriever.

Extended Data Fig. 5.

(A & D) Overlay of all 25 AlphaFold Multimer models of Retriever alone (A) or CCDC22-CCDC93-Retriever (D) with the cryo-EM model of Retriever. AFM models of Retriever are grey. (B & E) Representative AFM models colored using pLDDT scores. High scores indicate high reliability in local structure prediction. (C & F) PAE score matrix of the AFM model shown in (B & E). Low scores (deep color) indicate high reliability in the relative position in the 3D space. Boundaries of protein sequences and important structure regions are indicated.