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. 2023 Jun 20;19(6):e1011462. doi: 10.1371/journal.ppat.1011462

Table 2. EC50 values of Δ4-DA, Δ7-DA and CA for Dim, Bma, Hco and CelDAF-12.

EC50 and the logEC50 standard errors (SE) values were calculated from the nonlinear regression fits (sigmoidal dose-response with variable slope) of technical triplicates presented in Fig 2. nc: not calculated.

EC50 (logEC50 SE), nM
DimDAF-12 BmaDAF-12 CelDAF-12 HcoDAF-12
Δ4-dafachronic acid 1.2 (0.05) 1.7 (0.03) 38 (0.03) 87 (0.06)
Δ7-dafachronic acid 1.0 (0.03) 1.8 (0.06) 11 (0.02) 12 (0.04)
Cholestenoic acid 192 (0.03) 241 (0.04) nc nc