Table 2. EC50 values of Δ4-DA, Δ7-DA and CA for Dim, Bma, Hco and CelDAF-12.
EC50 (logEC50 SE), nM | ||||
---|---|---|---|---|
DimDAF-12 | BmaDAF-12 | CelDAF-12 | HcoDAF-12 | |
Δ4-dafachronic acid | 1.2 (0.05) | 1.7 (0.03) | 38 (0.03) | 87 (0.06) |
Δ7-dafachronic acid | 1.0 (0.03) | 1.8 (0.06) | 11 (0.02) | 12 (0.04) |
Cholestenoic acid | 192 (0.03) | 241 (0.04) | nc | nc |