Table 2. Hydroxyurea Use Before and After New Treatment Guidelines.
Measure | Days’ supply hydroxyurea, No. (N = 12 565 person-y) | ||||
---|---|---|---|---|---|
Michigan (n = 2914 person-y) | New York (n = 9651 person-y) | ||||
Before release (n = 1472 person-y)a | After release (n= 1443 person-y)a | Before release (n = 3718 person-y)a | After release (n = 5933 person-y)a | ||
Minimum | 0 | 0 | 0 | 0 | |
Quartile 1 | 0 | 0 | 0 | 0 | |
Median | 0 | 0 | 0 | 0 | |
Quartile 3 | 0 | 60 | 148 | 240 | |
Mean (SD)b | 41.73 (89.88) | 52.73 (97.04) | 79.78 (125.32) | 108.37 (142.77) |
The prerelease period was 2010 to 2014 for Michigan and 2012 to 2014 for New York, and the postrelease period was 2015 to 2018.
Rankings were compared using Wilcoxon test. P < .001 for before vs after release in Michigan and New York.