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. 2023 Mar 24;6(3):e231077. doi: 10.1001/jamanetworkopen.2023.1077

Table 2. Characteristics of Propensity Score–Matched Patients With Penetrating Brain Injury From 2017 to 2019.

Variable No. (%) P value SMD
Overall ICP monitoring
Without With
No. of patients 466 (100) 233 (50.0) 233 (50.0) NA NA
Age, mean (SD), y 32.3 (12.2) 32.3 (12.2) 32.2 (12.2) .93 .01
Systolic BP, mean (SD), mm Hg 131.7 (32.2) 132.2 (33.7) 131.2 (30.7) .74 .03
Heart rate, mean (SD), bpm 99.2 (29.5) 99.4 (30.8) 99.0 (28.2) .88 .01
Oxygen saturation level on pulse oximeter, mean (SD), % 97.2 (6.6) 97.0 (6.7) 97.3 (6.6) .64 .04
ISS, median (IQR) 25.0 (20.0-29.0) 25.0 (20.0-29.0) 25.0 (20.0-29.0) .41 .01
Sex
Male 397 (85.2) 199 (85.4) 198 (85.0) .97 .05
Female 69 (14.8) 34 (14.6) 35 (15.0)
Total GCS score on arrival
3 280 (60.1) 143 (61.4) 137 (58.8) .78 .15
4 31 (6.7) 12 (5.2) 19 (8.2)
5 21 (4.5) 10 (4.3) 11 (4.7)
6 48 (10.3) 24 (10.3) 24 (10.3)
7 51 (10.9) 28 (12.0) 23 (9.9)
8 35 (7.5) 16 (6.9) 19 (8.2)
Total GCS score at 24 h
3 172 (36.9) 85 (36.5) 87 (37.3) .97 .09
4 33 (7.1) 16 (6.9) 17 (7.3)
5 20 (4.3) 12 (5.2) 8 (3.4)
6 62 (13.3) 31 (13.3) 31 (13.3)
7 108 (23.2) 54 (23.2) 54 (23.2)
8 71 (15.2) 35 (15.0) 36 (15.5)
Pupillary reactivity .67 .05
1 Pupil reactive 123 (26.4) 64 (27.5) 59 (25.3)
Both pupils reactive 343 (73.6) 169 (72.5) 174 (74.7)
No midline shift 284 (60.9) 138 (59.2) 146 (62.7) .51 .07
Firearm-related injury 432 (92.7) 214 (91.8) 218 (93.6) .59 .07
Year of data
2017 157 (33.7) 76 (32.6) 81 (34.8) NA NA
2018 160 (34.3) 79 (33.9) 81 (34.8)
2019 149 (32.0) 78 (33.5) 71 (30.5)
ICU LOS, median (IQR), d 10.0 (5.0-17.0) 7.0 (4.0-12.0) 15.0 (8.0-21.0) <.001 NA
Unfavorable outcome 266 (57.1) 135 (57.9) 131 (56.2) .78 NA
WOLST 94 (20.2) 48 (20.6) 46 (19.7) .91 .02
Mortality 167 (35.8) 95 (40.8) 72 (30.9) .03 NA

Abbreviations: BP, blood pressure; bpm, beats per minute; GCS, Glasgow Coma Scale (score range: 3-8); ICP, intracranial pressure; ICU LOS, intensive care unit length of stay; ISS, Injury Severity Score; NA, not applicable; SMD, standardized mean difference; WOLST, withdrawal of life-sustaining therapy.