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. Author manuscript; available in PMC: 2023 Jun 30.
Published in final edited form as: Ann Appl Stat. 2020 Apr 16;14(1):433–451. doi: 10.1214/19-aoas1312

Table 1.

Joint Analysis of the GWAS summary statistics of three lipids levels in the K:1 multiple phenotype setting. The three lipids levels include HDL, LDL and TG. We use Z(P) as an estimate of the direction of β. The angle between Z(P) and uk(P) is estimated as θˆk(P). SNPs with the smallest five principal angles θˆ3(P) as well as the SNPs with the five largest principal angles θˆ3(P) are displayed

SNP CHR MinP pval V1(P) pval V3(P) pval Q(P) pval θˆ1(P) θˆ3(P)
rs7257916 19 2.19E-05 8.24E-01 2.90E-18 1.38E-19 87.52 6.21
rs13210634 6 5.58E-04 3.68E-01 9.61E-09 3.89E-09 75.51 20.56
rs804267 8 6.49E-05 1.72E-01 6.08E-09 2.90E-09 68.23 21.79
rs531117 11 1.51E-04 3.77E-01 1.25E-08 2.95E-09 76.25 25.92
rs1233489 6 7.83E-04 3.44E-01 2.07E-08 3.69E-09 75.44 28.98
rs6124245 20 1.42E-06 3.45E-03 9.04E-01 4.89E-04 48.84 89.10
rs2168711 18 1.14E-07 1.30E-06 8.28E-01 1.79E-04 29.86 88.69
rs12673863 7 1.11E-07 3.61E-03 8.28E-01 1.31E-04 51.95 88.45
rs7826687 8 8.08E-07 5.56E-09 7.32E-01 1.11E-03 4.35 88.03
rs17625826 2 1.22E-04 9.58E-08 5.49E-01 1.70E-03 11.64 86.29