Table 3.
Prediction of CAD presence and severe CAD of the study population.
| Variables | Prediction of CAD presence | Prediction of 3-vessel or LM disease | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||||||||
| HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age | 1.04 | 0.99–1.10 | 0.161 | 1.04 | 0.98–1.10 | 0.235 | 1.05 | 0.99–1.11 | 0.071 | 1.05 | 0.99–1.11 | 0.092 |
| Male | 1.13 | 0.44–2.92 | 0.801 | 1.06 | 0.37–3.05 | 0.914 | 1.33 | 0.54–3.24 | 0.535 | 1.29 | 0.47–3.54 | 0.618 |
| BMI | 0.93 | 0.77–1.12 | 0.448 | 0.93 | 0.76–1.14 | 0.476 | 0.88 | 0.73–1.05 | 0.160 | 0.85 | 0.70–1.05 | 0.124 |
| Diabetes | 3.26 | 0.90–11.78 | 0.071 | 3.52 | 0.91–13.61 | 0.068 | – | – | – | – | – | – |
| hs-CRP | 1.43 | 0.98–2.06 | 0.061 | 1.08 | 0.76–1.54 | 0.657 | 1.08 | 1.01–1.16 | 0.019 | 1.05 | 0.72–1.12 | 0.230 |
| miR-183-5p | 0.004* | 0.024* | 0.020* | 0.020* | ||||||||
| Low tertile | 1.00 | – | – | 1.00 | – | – | 1.00 | – | – | 1.00 | – | – |
| Middle tertile | 3.86 | 1.17–12.77 | 0.027 | 3.81 | 1.07–13.56 | 0.039 | 2.24 | 0.50–10.00 | 0.291 | 2.11 | 0.46–9.70 | 0.34 |
| High tertile | 18.86 | 2.37–149.79 | 0.005 | 14.57 | 1.38–153.65 | 0.026 | 8.64 | 2.32–32.26 | 0.001 | 6.59 | 1.59–27.25 | 0.009 |
Variables in the left column included in the logistics regression analysis.
CAD, coronary artery disease; HR, hazard ratio; CI, confidence interval; BMI, body mass index; hs-CRP, hypersensitive-C-reactive protein.
*Indicated p-value for trend in the logistics regression analysis.