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. 2023 Jun 30;6:681. doi: 10.1038/s42003-023-05052-1

Fig. 1. Analysis of Ras mutations and design of universal pegRNAs to correct the KRAS mutations.

Fig. 1

a Classification of all RAS gene family mutations, the left side, and subdivision of KRAS mutations, the right side. b Schematic overviews of KRAS corrections by universal pegRNAs. The G12 and G13 positions of KRAS and the PAM sequences of two universal pegRNAs are highlighted in red and blue, respectively.