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. 2023 Jun 30;6:681. doi: 10.1038/s42003-023-05052-1

Table 1.

Targetability of 12 KRAS mutations by ABE and PE systems.

KRAS mutations Counts Ratio (%) Targetability
Amino acids Nucleotides ABE PE
p.G12D c.35 G > A 16317 35.4
p.G12V c.35 G > T 11202 24.3
p.G13D c.38 G > A 6076 13.2
p.G12C c.34 G > T 5471 11.9
p.G12A c.35 G > C 2555 5.5
p.G12S c.34 G > A 2105 4.6
p.G12R c.34 G > C 1603 3.5
p.G13C c.37 G > T 425 0.9
p.G13S c.37 G > A 90 0.2
p.G13R c.37 G > C 74 0.2
p.G12F c.34_35delinsTT 62 0.1
p.G13A c.38 G > C 42 0.1
p.G13V c.38 G > T 39 0.1
Total counts 46,061 24,588 46,061