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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Curr Opin Nephrol Hypertens. 2023 Mar 20;32(4):305–312. doi: 10.1097/MNH.0000000000000888

Figure 3.

Figure 3.

Polygenic risk score-stratified analysis for Mendelian randomization study of FGF23 and heart failure. Figure: An eGFR polygenic risk score was developed using summary statistics from the Chronic Kidney Disease Genetics Consortium (CKDGen) genome-wide association study of eGFR in >1 million individuals and stratified MR analyses of FGF23 and heart failure were performed across eGFR polygenic risk score strata.