Table 1.
Lifetime model inputs
| Parameter | Value used | Distribution | Source |
| Mean age MT and IVT (years) | 76.15 | Beta | RESCUE10 |
| General death rate of population | Country-dependent values | Not applicable | WHO |
| HR of dying mRS score 0 | 1.53 | Log-normal | Hong et al 11 |
| HR of dying mRS score 1 | 1.52 | Log-normal | Hong et al 11 |
| HR of dying mRS score 2 | 2.17 | Log-normal | Hong et al 11 |
| HR of dying mRS score 3 | 3.18 | Log-normal | Hong et al 11 |
| HR of dying mRS score 4 | 4.50 | Log-normal | Hong et al 11 |
| HR of dying mRS score 5 | 6.55 | Log-normal | Hong et al 11 |
| Quarterly recurrence risk from mRS score 0–5 (3–12 months) | 1.66% | Dirichlet | Slot et al 12 |
| Quarterly recurrence risk from mRS score 0–5 (> 12 months) | 0.51% | Dirichlet | Slot et al 12 |
| Quarterly recurrence risk after a recurrent stroke from mRS score 0–5 | 1.30% | Dirichlet | Ganesalingam et al 13 |
| Transition probability to mRS score 1 if mRS score 0 | 18.71% | Beta | Fagan et al 14 |
| Transition probability to mRS score 2 if mRS score 0 | 18.71% | Beta | Fagan et al 14 |
| Transition probability to mRS score 3 if mRS score 0 | 18.71% | Beta | Fagan et al 14 |
| Transition probability to mRS score 4 if mRS score 0 | 18.71% | Beta | Fagan et al 14 |
| Transition probability to mRS score 5 if mRS score 0 | 18.71% | Beta | Fagan et al 14 |
| Transition probability to mRS score 6 if mRS score 0 | 5.13% | Beta | Fagan et al 14 |
| Transition probability to mRS score 2 if mRS score 1 | 23.39% | Beta | Fagan et al 14 |
| Transition probability to mRS score 3 if mRS score 1 | 23.39% | Beta | Fagan et al 14 |
| Transition probability to mRS score 4 if mRS score 1 | 23.39% | Beta | Fagan et al 14 |
| Transition probability to mRS score 5 if mRS score 1 | 23.39% | Beta | Fagan et al 14 |
| Transition probability to mRS score 6 if mRS score 1 | 5.13% | Beta | Fagan et al 14 |
| Transition probability to mRS score 3 if mRS score 2 | 31.19% | Beta | Fagan et al 14 |
| Transition probability to mRS score 4 if mRS score 2 | 31.19% | Beta | Fagan et al 14 |
| Transition probability to mRS score 5 if mRS score 2 | 31.19% | Beta | Fagan et al 14 |
| Transition probability to mRS score 6 if mRS score 2 | 5.13% | Beta | Fagan et al 14 |
| Transition probability to mRS score 4 if mRS score 3 | 46.79% | Beta | Fagan et al 14 |
| Transition probability to mRS score 5 if mRS score 3 | 46.79% | Beta | Fagan et al 14 |
| Transition probability to mRS score 6 if mRS score 3 | 5.13% | Beta | Fagan et al 14 |
| Transition probability to mRS score 5 if mRS score 4 | 93.57% | Beta | Fagan et al 14 |
| Transition probability to mRS score 6 if mRS score 4 | 5.13% | Beta | Fagan et al 14 |
| Transition probability to mRS score 6 if mRS score 5 | 98.70% | Beta | Fagan et al 14 |
IVT, IV thrombolysis; mRS, modified Rankin Scale; MT, mechanical thrombectomy.