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. 2023 Feb 21;94(7):560–566. doi: 10.1136/jnnp-2022-330608

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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IEPD comparisons by beeswarm plot for (A-C) pRNFL and (D-F) GCIPL in (A, D) all NMOSD-ON patients compared with HC and NMOSD-NON, (B, E) NMOSD-ON patients with the ON as their first attack compared with HC and NMOSD-NON and (C, F) NMOSD-ON and NMOSD-NON patients with a disease duration <10 years compared with HC. GCIPL, combined ganglion cell and inner plexiform layer; HC, healthy controls; IEPD, intereye percentage difference; NMOSD-ON, patients with aquaporin-4-antibody seropositive neuromyelitis optica spectrum disorders and a history of unilateral optic neuritis; NMOSD-NON, patients with aquaporin-4-antibody seropositive neuromyelitis optica spectrum disorders and no history of optic neuritis; pRNFL, peripapillary retina nerve fibre layer.