Table 2.

Comparison of IEAD and IEPD value for GCIPL and pRNFL

	NMOSD-ON versus HC		NMOSD-ON versus NMOSD-NON
	T value	P value	T value	P value
All subjects
pRNFL IEPD (%)	−6.885	<0.001	−6.519	<0.001
pRNFL IEAD (µm)	−6.483	<0.001	−5.102	<0.001
GCIPL IEPD (%)	−6.566	<0.001	−6.928	<0.001
GCIPL IEAD (µm)	−6.338	<0.001	−5.663	<0.001
First attack only
pRNFL IEPD (%)	−6.162	<0.001	−5.892	<0.001
pRNFL IEAD (µm)	−5.969	<0.001	−5.677	<0.001
GCIPL IEPD (%)	−6.570	<0.001	−6.024	<0.001
GCIPL IEAD (µm)	−6.357	<0.001	−5.778	<0.001
Recent onset (<10 years)
pRNFL IEPD (%)	−6.527	<0.001	−6.201	<0.001
pRNFL IEAD (µm)	−6.054	<0.001	−5.708	<0.001
GCIPL IEPD (%)	−5.768	<0.001	−5.274	<0.001
GCIPL IEAD (µm)	−5.530	<0.001	−5.014	<0.001

GCIPL, combined ganglion cell and inner plexiform layer; HC, healthy control; IEAD, intereye absolute difference; IEPD, intereye percentage difference; NMOSD-NON, patients with aquaporin-4-antibody seropositive neuromyelitis optica spectrum disorders and no history of optic neuritis; NMOSD-ON, patients with aquaporin-4-antibody seropositive neuromyelitis optica spectrum disorders and a history of unilateral optic neuritis; ON, optic neuritis; pRNFL, peripapillary retinal nerve fibre layer.