Figure 2.

NFKBIA deletions and survival in patients with lower-grade gliomas

(A−B) Kaplan-Meier estimates of overall survival (A) and recurrence-free survival (B) for 508 and 425 patients in population 1, respectively, with patients stratified according to the presence (del) or absence (wild-type, wt) of the NFKBIA deletion. CI denotes confidence interval. Small vertical lines indicate patients alive at last follow-up assessment. p values were calculated using the Cox model likelihood-ratio test. Patients at risk (No. at Risk) correspond to the x axis timescale.

(C and D) Kaplan-Meier estimates for the relationship between NFKBIA deletions and patient overall survival (C) and recurrence-free survival (D) in 87 low-grade gliomas patients of NRG/RTOG consortium trial 9802 (population 2).

(E) Kaplan-Meier estimates for the relationship between NFKBIA deletions and overall survival in population 3.