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. 2023 Jun 9;60:102017. doi: 10.1016/j.eclinm.2023.102017

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© 2023 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Forest plots for PET/CT pre maintenance for PFS (a) and OS (b). ∗High-risk cytogenetics were defined in accordance with the International Myeloma Working Group (IMWG) criteria: presence of t (4; 14) and/or t (14; 16) and/or del (17p). Abbreviations. ASCT, Autologous stem-cell transplantation; CI, Confidence interval; HR, Hazard ratio; IMWG, International myeloma working group; ISS, International staging system stage; ITT, Intention to treat; MRD, Minimal residual disease; KCd, carfilzomib-cyclophosphamide-dexamethasone; MEL200, melphalan at 200 mg/m²; KCd plus ASCT, 4 KCd induction cycles, MEL200-ASCT, 4 KCd consolidation cycles; KRd, carfilzomib-lenalidomide-dexamethasone; KRd12, 12 KRd cycles without ASCT; KRd plus ASCT, 4 KRd induction cycles, MEL200-ASCT, 4 KRd consolidation cycles; OS, Overall survival; P, P-value; PET/CT, positron emission tomography/computed tomography; PFS, Progression-free survival; R1, first randomisation (induction-intensification-consolidation treatment).