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. 2023 Jun 1;15(6):e39816. doi: 10.7759/cureus.39816

Table 4. Clinical characteristics of XBB.1.16* and other Omicron lineages in Maharashtra.

Clinical Characteristics XBB.1.16* Other Omicron Lineages Grand Total p-value
XBB.1.16 XBB.1.16.1
History of prior COVID-19 infection 0.010
Present 21 (10.7%) 9 (11.3%) 23 (20.9%) 53 (13.7%)  
Absent 175 (89.3%) 71 (88.7%) 87 (79.1%) 333 (86.3%)  
Symptom status at the time of acute infection 0.125
Asymptomatic 16 (8.2%) 6 (7.5%) 4 (3.6%) 26 (6.7%)  
Symptomatic 180 (91.8%) 74 (92.5%) 106 (96.4%) 360 (93.3%)  
Presence of any comorbidity 0.114
No comorbidity 161 (82.1%) 66 (82.5%) 97 (88.2%) 324 (83.9%)  
Presence of one comorbid condition 24 (12.3%) 10 (12.5%) 12 (10.9%) 46 (11.9%)  
Presence of two or more comorbid conditions 11 (5.6%) 4 (5.0%) 1 (0.9%) 16 (4.2%)  
Initial presenting symptoms  
Fever 127 (64.8%) 58 (72.5%) 76 (69.1%) 261 (67.6%) 0.696
Cough 85 (43.4%) 31 (38.8%) 39 (35.5%) 155 (40.2%) 0.234
Rhinorrhoea 67 (34.2%) 26 (32.5%) 39 (35.5%) 132 (34.2%) 0.742
Fatigue 27 (13.8%) 12 (15.0%) 19 (17.3%) 58 (15.0%) 0.435
Body ache 28 (14.3%) 12 (15.0%) 13 (11.8%) 53 (13.7%) 0.491
Headache 22 (11.2%) 6 (7.5%) 16 (14.5%) 44 (11.4%) 0.219
Breathlessness 17 (8.7%) 6 (7.5%) 4 (3.6%) 27 (7.0%) 0.102
Sore Throat 7 (3.6%) 9 (11.3%) 11 (10.0%) 27 (7.0%) 0.144
Diarrhoea 7 (3.6%) 3 (3.8%) 1 (0.9%) 11 (2.8%) 0.190
Vomiting 3 (1.5%) 2 (2.5%) 3 (1.8%) 7 (1.8%) 1.000
Chest Pain 3 (1.5%) 0 1 (0.9%) 4 (1.0%) 1.000
Loss of taste and smell 4 (2.0%) 0 2 (1.8%) 6 (1.6%) 1.000
Increased Sweating 0 2 (2.5%) 2 (0.7%) 3 (0.8%) -
Reduced appetite 3 (1.5%) 0 0 3 (0.8%) -
Type of quarantine 0.018
Home quarantine 145 (74.0%) 60 (75.0%) 94 (85.5%) 299 (77.5%)  
Institutional quarantine/ Hospitalization 51 (26.0%) 20 (25.0%) 16 (14.5%) 87 (22.5%)  
Treatment  
a. Home Isolated 0.433
No treatment needed 3 (2.1%) 4 (6.7%) 1 (1.1%) 8 (2.7%)  
Needed Conservative treatment only 141 (97.2%) 56 (93.3%) 92 (97.8%) 289 (96.6%)  
Antiviral treatment taken 1 (0.7%) 0 1 (1.1%) 2 (0.7%)  
b. Institutional quarantine/ Hospitalization 0.633
Needed Conservative treatment only 34 (66.7%) 12 (60.0%) 10 (62.5%) 56 (64.4%)  
Needed Supplemental oxygen 17 (33.3%) 7 (35.0%) 6 (37.5%) 30 (34.5%)  
Mask 14 (82.3%) 7 (100%) 5 (83.3%) 26 (86.7%)  
Intubation 3 (17.7%) 0 1 (16.7%) 4 (13.3%)  
Needed antiviral/steroids/ Immunomodulatory drugs, along with oxygen therapy 0 1 (5.0%) 0 1 (1.1%)  
Outcome of disease 0.449
Alive 192 (98.0%) 77 (96.2%) 109 (99.1%) 378 (97.9%)  
Home quarantine 145 (75.5%) 59 (76.6%) 94 (86.2%) 298 (78.8%)  
Institutional quarantine/ Hospitalization 47 (24.5%) 18 (23.4%) 15 (13.8%) 80 (21.2%)  
Dead 4 (2.0%) 3 (3.8%) 1 (0.9%) 8 (2.1%)  
Home quarantine 0 1 (33.3%) 0 1 (12.5%)  
Institutional quarantine/ Hospitalization 4 (100%) 2 (66.7%) 1 (100%) 7 (87.5%)  
Vaccination Status 0.288
Not vaccinated 18 (9.2%) 05 (6.2%) 13 (11.8%) 36 (9.3%)  
Vaccinated 178 (90.8%) 75 (93.8%) 97 (88.2%) 350 (90.7%)  
Vaccinated with one dose 13 (7.3%) 2 (2.7%) 2 (2.1%) 17 (4.9%)  
Vaccinated with two doses 144 (80.9%) 52 (69.3%) 69 (71.1%) 265 (75.7%)  
Vaccinated with precautionary dose (Booster dose) 21 (11.8%) 21 (28.0%) 26 (26.8%) 68 (19.4%)