Table 3.
Screening outcome | Treatment offered | Rifamycin component |
Leprosy | Leprosy MDT | Monthly rifampicin for 6–12 months |
TB | TB treatment | Daily rifampicin for 6–12 months |
RR-TB | DR-TB treatment+SDR | Single dose rifampicin |
Eligible for TPT | 3HP or 3RH | Weekly rifapentine or daily rifampicin for 3 months |
Leprosy HHC | SDR-PEP | Rifampicin given at baseline and 1 year later |
None of the above | SDR-MDA | Single dose of rifampicin |
Screening outcomes are exhaustive but not mutually exclusive. The rifamycin component of each treatment strategy includes sufficient exposure to offer prevention for leprosy, in effect a MDA of leprosy chemoprophylaxis.
DR-TB, drug-resistant tuberculosis; HHC, household contact; 3HP, 3-months of weekly rifapentine and isoniazid; MDA, mass drug administration; MDT, multidrug treatment; NLP, national leprosy program; PCR, polymerase chain reaction; PEP, postexposure prophylaxis; 3RH, 3-months of daily rifampicin and isoniazid; RR-TB, rifampicin-resistant tuberculosis; SDR, single-dose rifampicin; TB, tuberculosis; TPT, tuberculosis preventive treatment.