Table 2.
Main causes of death for patients with localized kidney cancer
| Causes of death | Total | Clear cell RCC | Non-clear cell RCC | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Observed, n | Expected, n | SMR (95% CI) | Observed, n | Expected, n | SMR (95% CI) | Observed, n | Expected, n | SMR (95% CI) | |
| All causes of death | 30,390 | 19,151.73 | 1.59# (1.57–1.6) | 12,549 | 8,512.19 | 1.47# (1.45–1.5) | 17,841 | 10,639.55 | 1.68# (1.65–1.7) |
| All malignant cancers | 12,022 | 4,575.66 | 2.63# (2.58–2.67) | 5,118 | 2,095.27 | 2.44# (2.38–2.51) | 6,904 | 2,480.39 | 2.78# (2.72–2.85) |
| Urinary system | 7,500 | 260.56 | 28.78# (28.14–29.44) | 3,267 | 117.66 | 27.77# (26.82–28.74) | 4,233 | 142.9 | 29.62# (28.74–30.53) |
| Kidney and renal pelvis | 7,161 | 111.5 | 64.22# (62.74–65.73) | 3,220 | 51.54 | 62.48# (60.34–64.67) | 3,941 | 59.96 | 65.73# (63.69–67.81) |
| Urinary bladder | 277 | 141.91 | 1.95# (1.73–2.2) | 44 | 62.87 | 0.70# (0.51–0.94) | 233 | 79.03 | 2.95# (2.58–3.35) |
| Respiratory system | 1,315 | 1,318.67 | 1 (0.94–1.05) | 538 | 606.11 | 0.89# (0.81–0.97) | 777 | 712.56 | 1.09# (1.02–1.17) |
| Lung and bronchus | 1,283 | 1,277.13 | 1 (0.95–1.06) | 529 | 587.53 | 0.90# (0.83–0.98) | 754 | 689.6 | 1.09# (1.02–1.17) |
| Digestive system | 1,276 | 1,176.37 | 1.08# (1.03–1.15) | 566 | 540.52 | 1.05 (0.96–1.14) | 710 | 635.85 | 1.12# (1.04–1.2) |
| Pancreas | 393 | 308.78 | 1.27# (1.15–1.41) | 174 | 143.53 | 1.21# (1.04–1.41) | 219 | 165.25 | 1.33# (1.16–1.51) |
| Colon and rectum | 315 | 403.3 | 0.78# (0.7–0.87) | 140 | 181.26 | 0.77# (0.65–0.91) | 175 | 222.04 | 0.79# (0.68–0.91) |
| Liver and intrahepatic bile duct | 275 | 183.41 | 1.50# (1.33–1.69) | 126 | 86.78 | 1.45# (1.21–1.73) | 149 | 96.63 | 1.54# (1.3–1.81) |
| Male genital system | 183 | 324.19 | 0.56# (0.49–0.65) | 72 | 132.98 | 0.54# (0.42–0.68) | 111 | 191.22 | 0.58# (0.48–0.7) |
| Prostate | 178 | 319.62 | 0.56#(0.48–0.65) | 71 | 130.87 | 0.54# (0.42–0.68) | 107 | 188.74 | 0.57# (0.46–0.69) |
| Brain and other nervous system | 159 | 100.52 | 1.58#(1.35–1.85) | 68 | 49.1 | 1.38# (1.08–1.76) | 91 | 51.42 | 1.77# (1.42–2.17) |
| Leukemia | 190 | 182.42 | 1.04 (0.9–1.2) | 72 | 82.78 | 0.87 (0.68–1.1) | 118 | 99.64 | 1.18 (0.98–1.42) |
| Lymphoma | 148 | 173.82 | 0.85 (0.72–1) | 62 | 79.52 | 0.78# (0.6–1) | 86 | 94.3 | 0.91 (0.73–1.13) |
| Non-tumor causes | |||||||||
| Diseases of heart | 6,161 | 4,945.61 | 1.25# (1.21–1.28) | 2,547 | 2,140.78 | 1.19# (1.14–1.24) | 3,614 | 2,804.84 | 1.29# (1.25–1.33) |
| COPD and allied cond | 1,185 | 1,194.07 | 0.99 (0.94–1.05) | 470 | 543.39 | 0.86# (0.79–0.95) | 715 | 650.67 | 1.10# (1.02–1.18) |
| Cerebrovascular diseases | 1,183 | 1,058.31 | 1.12# (1.06–1.18) | 480 | 455.48 | 1.05 (0.96–1.15) | 703 | 602.83 | 1.17# (1.08–1.26) |
| Nephritis, nephrotic syndrome and nephrosis | 1,166 | 387.89 | 3.01# (2.84–3.18) | 409 | 165.73 | 2.47# (2.23–2.72) | 757 | 222.16 | 3.41# (3.17–3.66) |
| Diabetes mellitus | 1,137 | 595.36 | 1.91# (1.8–2.02) | 488 | 265.59 | 1.84# (1.68–2.01) | 649 | 329.77 | 1.97# (1.82–2.13) |
| Accidents and adverse effects | 668 | 602.41 | 1.11# (1.03–1.2) | 293 | 282.38 | 1.04 (0.92–1.16) | 375 | 320.03 | 1.17# (1.06–1.3) |
| Alzheimer’s | 611 | 701.64 | 0.87# (0.8–0.94) | 242 | 300.21 | 0.81# (0.71–0.91) | 369 | 401.43 | 0.92 (0.83–1.02) |
| Pneumonia and influenza | 489 | 429.8 | 1.14# (1.04–1.24) | 197 | 184.8 | 1.07 (0.92–1.23) | 292 | 245 | 1.19# (1.06–1.34) |
| Hypertension without heart disease | 482 | 223.68 | 2.15# (1.97–2.36) | 192 | 96.06 | 2.00# (1.73–2.3) | 290 | 127.62 | 2.27# (2.02–2.55) |
| Septicemia | 406 | 285.54 | 1.42# (1.29–1.57) | 164 | 125.48 | 1.31# (1.11–1.52) | 242 | 160.05 | 1.51# (1.33–1.71) |
| Chronic liver disease and cirrhosis | 293 | 220.44 | 1.33# (1.18–1.49) | 149 | 110.01 | 1.35# (1.15–1.59) | 144 | 110.44 | 1.30# (1.1–1.54) |
| Suicide and self-inflicted injury | 151 | 153.78 | 0.98 (0.83–1.15) | 83 | 78.18 | 1.06 (0.85–1.32) | 68 | 75.61 | 0.9 (0.7–1.14) |
SMR standardized mortality ratio, CI confidence interval, COPD chronic obstructive pulmonary disease
#Statistical significance with P < 0.05