Table 3.
Main causes of deaths for patients with regional kidney cancer
| Causes of deaths | Total | Clear cell RCC | Non-clear cell RCC | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Observed, n | Expected, n | SMR (95% CI) | Observed, n | Expected, n | SMR (95% CI) | Observed, n | Expected, n | SMR (95% CI) | |
| All causes of death | 14,437 | 4,292.43 | 3.36# (3.31–3.42) | 5,660 | 1,983.35 | 2.85# (2.78–2.93) | 8,777 | 2,309.08 | 3.80# (3.72–3.88) |
| All malignant cancers | 10,352 | 1,016.84 | 10.18# (9.99–10.38) | 3,918 | 487.27 | 8.04# (7.79–8.3) | 6,434 | 529.57 | 12.15# (11.85–12.45) |
| Urinary system | 8,746 | 61.07 | 143.22# (140.24–146.26) | 3,423 | 29.15 | 117.44# (113.54–121.44) | 5,323 | 31.92 | 166.77# (162.32–171.31) |
| Kidney and renal pelvis | 8,240 | 25.34 | 325.20# (318.21–332.3) | 3,410 | 12.36 | 275.95# (266.77–285.37) | 4,830 | 12.98 | 372.08# (361.66–382.72) |
| Urinary bladder | 371 | 34.05 | 10.90# (9.81–12.06) | 10 | 15.99 | 0.63 (0.3–1.15) | 361 | 18.06 | 19.99# (17.98–22.16) |
| Ureter | 57 | 0.8 | 71.17# (53.91–92.21) | 0 | 0.38 | 0 (0–9.7) | 57 | 0.42 | 135.53# (102.65–175.59) |
| Respiratory system | 354 | 295.99 | 1.20# (1.07–1.33) | 145 | 142.81 | 1.02 (0.86–1.19) | 209 | 153.19 | 1.36# (1.19–1.56) |
| Lung and bronchus | 346 | 286.72 | 1.21# (1.08–1.34) | 140 | 138.32 | 1.01 (0.85–1.19) | 206 | 148.41 | 1.39# (1.2–1.59) |
| Digestive System | 311 | 259.38 | 1.20# (1.07–1.34) | 119 | 125.56 | 0.95 (0.79–1.13) | 192 | 133.83 | 1.43# (1.24–1.65) |
| Pancreas | 106 | 67.4 | 1.57# (1.29–1.9) | 36 | 32.89 | 1.09 (0.77–1.52) | 70 | 34.51 | 2.03# (1.58–2.56) |
| Colon and rectum | 87 | 89.3 | 0.97 (0.78–1.2) | 35 | 41.94 | 0.83 (0.58–1.16) | 52 | 47.36 | 1.1 (0.82–1.44) |
| Liver and intrahepatic bile duct | 48 | 39.77 | 1.21 (0.89–1.6) | 23 | 20.15 | 1.14 (0.72–1.71) | 25 | 19.61 | 1.27 (0.82–1.88) |
| Male genital system | 46 | 78.63 | 0.59# (0.43–0.78) | 18 | 35.37 | 0.51# (0.3–0.8) | 28 | 43.26 | 0.65# (0.43–0.94) |
| Prostate | 43 | 77.58 | 0.55# (0.4–0.75) | 17 | 34.85 | 0.49# (0.28–0.78) | 26 | 42.73 | 0.61# (0.4–0.89) |
| Soft tissue including heart | 50 | 6.27 | 7.98# (5.92–10.51) | 2 | 3.08 | 0.65 (0.08–2.35) | 48 | 3.19 | 15.05# (11.1–19.96) |
| Brain and other nervous system | 44 | 22 | 2.00# (1.45–2.68) | 21 | 11.15 | 1.88# (1.17–2.88) | 23 | 10.86 | 2.12# (1.34–3.18) |
| Leukemia | 35 | 42.31 | 0.83 (0.58–1.15) | 10 | 20.05 | 0.50# (0.24–0.92) | 25 | 22.25 | 1.12 (0.73–1.66) |
| Lymphoma | 29 | 40.39 | 0.72 (0.48–1.03) | 13 | 19.15 | 0.68 (0.36–1.16) | 16 | 21.24 | 0.75 (0.43–1.22) |
| Non-tumor causes | |||||||||
| Diseases of heart | 1,424 | 1,128.76 | 1.26# (1.2–1.33) | 607 | 509.76 | 1.19# (1.1–1.29) | 817 | 619 | 1.32# (1.23–1.41) |
| Cerebrovascular diseases | 289 | 238.34 | 1.21# (1.08–1.36) | 129 | 105.6 | 1.22# (1.02–1.45) | 160 | 132.73 | 1.21# (1.03–1.41) |
| COPD and allied cond | 266 | 274.97 | 0.97 (0.85–1.09) | 104 | 129.15 | 0.81# (0.66–0.98) | 162 | 145.82 | 1.11 (0.95–1.3) |
| Diabetes mellitus | 227 | 129.1 | 1.76# (1.54–2) | 112 | 60.84 | 1.84# (1.52–2.22) | 115 | 68.25 | 1.68# (1.39–2.02) |
| Nephritis, nephrotic syndrome and nephrosis | 210 | 85.61 | 2.45# (2.13–2.81) | 90 | 38.64 | 2.33# (1.87–2.86) | 120 | 46.97 | 2.56# (2.12–3.06) |
| Pneumonia and influenza | 138 | 100 | 1.38# (1.16–1.63) | 48 | 44.17 | 1.09 (0.8–1.44) | 90 | 55.82 | 1.61# (1.3–1.98) |
| Alzheimer’s | 130 | 159.43 | 0.82# (0.68–0.97) | 60 | 69.31 | 0.87 (0.66–1.11) | 70 | 90.13 | 0.78# (0.61–0.98) |
| Accidents and adverse effects | 130 | 128.41 | 1.01 (0.85–1.2) | 53 | 61.93 | 0.86 (0.64–1.12) | 77 | 66.49 | 1.16 (0.91–1.45) |
| Septicemia | 108 | 61.91 | 1.74# (1.43–2.11) | 39 | 28.59 | 1.36 (0.97–1.86) | 69 | 33.32 | 2.07# (1.61–2.62) |
| Hypertension without heart disease | 89 | 47.89 | 1.86# (1.49–2.29) | 37 | 21.55 | 1.72# (1.21–2.37) | 52 | 26.34 | 1.97# (1.47–2.59) |
| Chronic liver disease and cirrhosis | 65 | 45.89 | 1.42# (1.09–1.81) | 35 | 24.07 | 1.45# (1.01–2.02) | 30 | 21.82 | 1.37 (0.93–1.96) |
| Suicide and self-inflicted injury | 33 | 32.71 | 1.01 (0.69–1.42) | 15 | 17.1 | 0.88 (0.49–1.45) | 18 | 15.62 | 1.15 (0.68–1.82) |
SMR standardized mortality ratio, CI confidence interval, COPD chronic obstructive pulmonary disease
#Statistical significance with P < 0.05