Table 6.
Univariable and multivariable analysis for factors associated with hospital MACCE in emergency and non-emergency left main revascularization
| Hospital MACCE | Univariable | Multivariable | ||
|---|---|---|---|---|
| Emergency revascularization | OR (95% CI) | P | OR (95% CI) | P |
| Baseline characteristics | ||||
| Male | 1.90 (1.05–3.44) | 0.033 | – | – |
| Age | 1.02 (0.99–1.04) | 0.111 | – | – |
| Body mass index | 0.99 (0.93–1.04) | 0.642 | – | – |
| Smoking | 0.85 (0.49–1.47) | 0.561 | – | – |
| Diabetes mellitus | 0.96 (0.54–1.69) | 0.887 | – | – |
| Dyslipidemia | 1.02 (0.59–1.78) | 0.936 | – | – |
| Hypertension | 1.89 (1.03–3.44) | 0.038 | – | – |
| Previous myocardial infarction | 1.77 (1.04–3.01) | 0.037 | – | – |
| Chronic kidney disease | 3.57 (2.04–6.24) | < 0.001 | 2.99 (1.62–5.50) | < 0.001 |
| Peripheral arterial disease | 3.22 (1.63–6.33) | 0.001 | 2.45 (1.17–5.13) | 0.017 |
| Cerebrovascular accident | 2.09 (0.97–4.50) | 0.059 | – | – |
| Congestive heart failure | 3.88 (2.13–7.06) | < 0.001 | 2.67 (1.37–5.19) | 0.004 |
| Atrial fibrillation | 1.92 (0.85–4.24) | 0.109 | – | – |
| Ejection fraction category | 1.03 (0.74–1.41) | 0.874 | – | – |
| PCI vs. CABG | 1.01 (0.60–1.71) | 0.974 | – | – |
| EuroSCORE | ||||
| EuroSCORE | 1.08 (1.04–1.10) | < 0.001 | 2.69 (1.82–3.97) | < 0.001 |
| PCI vs. CABG | 1.01 (0.60–1.71) | 0.974 | 0.79 (0.45–1.38) | 0.409 |
| Presentation | ||||
| Arrest | 4.72 (2.63–8.50) | < 0.001 | 2.16 (1.11–4.22) | 0.024 |
| Shock | 8.73 (4.87–15.64) | < 0.001 | 8.69 (4.47–16.92) | < 0.001 |
| STEMI | 0.26 (0.14–0.67) | < 0.001 | – | – |
| NSTEMI | 0.24 (0.13–0.44) | < 0.001 | – | – |
| PCI vs. CABG | 1.01 (0.60–1.71) | 0.974 | 0.46 (0.24–0.87) | 0.017 |
| SYNTAX score | ||||
| SYNTAX score | 1.02 (0.99–1.04) | 0.158 | 1.38 (0.95–1.99) | 0.091 |
| PCI vs. CABG | 1.01 (0.60–1.71) | 0.974 | 1.14 (0.66–1.96) | 0.641 |
| Non–emergency revascularization | ||||
| Baseline characteristics | ||||
| Male | 1.20 (0.66–2.19) | 0.542 | – | – |
| Age | 1.01 (0.98–1.03) | 0.553 | – | – |
| Body mass index | 0.97 (0.92–1.02) | 0.232 | – | – |
| Smoking | 0.93 (0.55–1.59) | 0.796 | – | – |
| Diabetes mellitus | 1.16 (0.65–2.05) | 0.618 | – | – |
| Dyslipidemia | 2.79 (1.31–5.93) | 0.008 | 2.36 (1.22–5.57) | 0.013 |
| Hypertension | 1.68 (0.86–3.27) | 0.127 | – | – |
| Previous myocardial infarction | 1.23 (0.71–2.15) | 0.461 | – | – |
| Chronic kidney disease | 1.33 (0.73–2.42) | 0.350 | – | – |
| Peripheral arterial disease | 1.01 (0.45–2.25) | 0.989 | – | – |
| Cerebrovascular accident | 0.59 (0.21–1.65) | 0.317 | – | – |
| Congestive heart failure | 1.59 (0.79–3.19) | 0.192 | 2.36 (1.10–5.04) | 0.027 |
| Atrial fibrillation | – | – | – | – |
| Ejection fraction category | 0.80 (0.59–1.08) | 0.148 | – | – |
| PCI vs. CABG | 0.27 (0.15–0.48) | < 0.001 | 0.30 (0.16–0.56) | < 0.001 |
| EuroSCORE | ||||
| EuroSCORE | 1.06 (1.02–1.12) | 0.005 | 1.07 (1.03–1.11) | 0.001 |
| PCI vs. CABG | 0.27 (0.15–0.48) | < 0.001 | 0.25 (0.14–0.45) | < 0.001 |
| Presentation | ||||
| Arrest | – | – | – | – |
| Shock | – | – | – | – |
| STEMI | – | – | – | – |
| NSTEMI | 0.62 (0.35–1.11) | 0.107 | – | – |
| PCI vs. CABG | 0.27 (0.15–0.48) | < 0.001 | – | – |
| SYNTAX score | ||||
| SYNTAX score | 1.02 (0.99–1.05) | 0.117 | 1.17 (0.79–1.73) | 0.444 |
| PCI vs. CABG | 0.27 (0.15–0.48) | < 0.001 | 0.27 (0.15–0.50) | < 0.001 |
MACCE: major adverse cardiovascular and cerebrovascular events, CABG: coronary artery bypass graft surgery, PCI: percutaneous coronary intervention, EuroSCORE score: European system for cardiac operative risk evaluation, STEMI: ST–segment elevation myocardial infarction; NSTEMI: non-ST-segment elevation myocardial infarction, OR: odds ratio, CI: confidence interval