Table 2.
Association between VISTA expression in venous tumor thrombus/primary tumor and clinicopathological characteristics of RCC
| Feature | VISTA in venous tumor thrombus | VISTA in primary tumor | ||||
|---|---|---|---|---|---|---|
| Negative | Positive | p-value | Negative | Positive | p-value | |
| Sex | ||||||
| Female | 10 (28) | 26 (72) | 0.034 | 20 (54) | 17 (46) | 0.959 |
| Male | 23 (51) | 22 (49) | 23 (53) | 20 (47) | ||
| Tumor size | ||||||
| < 10 cm | 21 (43) | 28 (57) | 0.631 | 21 (44) | 27 (56) | 0.028 |
| > 10 cm | 12 (37) | 20 (63) | 22 (69) | 10 (31) | ||
| Nodal metastases | ||||||
| No | 28 (42) | 38 (58) | 0.518 | 33 (51) | 32 (49) | 0.265 |
| Yes | 5 (33) | 10 (67) | 10 (67) | 5 (33) | ||
| Distant metastases | ||||||
| No | 28 (48) | 30 (52) | 0.028 | 33 (58) | 24 (42) | 0.241 |
| Yes | 5 (22) | 18 (78) | 13 (57) | 10 (43) | ||
| Grade | ||||||
| 2–3 | 14 (52) | 13 (48) | 0.150 | 15 (56) | 12 (44) | 0.817 |
| 4 | 19 (35) | 35 (65) | 28 (53) | 25 (47) | ||
| Tumor necrosis | ||||||
| No | 23 (53) | 20 (47) | 0.013 | 24 (57) | 18 (43) | 0.522 |
| Yes | 10 (26) | 28 (74) | 19 (50) | 19 (50) | ||
p-values ≤ 0.05 were considered statistically significant (in bold)
p-values were calculated with the chi-square test
VISTA V-domain Ig suppressor of T cell activation. P values calculated with chi-square test