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. 2022 Aug 20;149(7):3739–3752. doi: 10.1007/s00432-022-04184-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Changing landscape of induction therapies prior to autologous stem cell transplantation in 540 patients divided into four cohorts over time from 1996 to 2019. VAD: vincristine, adriamycin and dexamethasone; VMP: bortezomib, melphalan and prednisone; BPV: bendamustine, prednisone and bortezomib, VD: bortezomib and dexamethasone; PAD: bortezomb, adriamycin and dexamethasone; VCD: bortezomid, cyclophosphamide and dexamethasone. Others: Regimens used up to and including 2010: VCAP (vincristine, cyclophosphamide, adriblastin, prednisolone), BP (bendamustine and prednisolone) and from 2011: VTD (bortezomib, thalidomide and dexamethasone), VRD (bortezomid, lenalidomide and dexamethasone), DVD (daratumumab, bortezomib and dexamethasone)