Fig. 3.

Correlation of FAP expression with immunosuppressive features in the TME of NSCLC. a Correlation of FAP expression between immune/stromal/ESTIMATE scores. b GSEA of FAP in LUAD and LUSC from the TCGA dataset. c Correlations between FAP and infiltrating levels of CD8 + T cells, CD4 + memory resting cells, Tregs, M2 macrophages, MDSCs, neutrophils, activated NK cells and activated DCs of LUAD and LUSC in the TIMER database. d Correlation of FAP expression with immune checkpoints and immunosuppressive genes in the TME of LUAD and LUSC in the TIMER database. e T cell exclusion score in the high- and low-FAP groups of LUAD and LUSC estimated by the TIDE framework. ***P < 0.001