Fig. 8.

Progressive impairment of retinal function in Apoj^−/− mice. A Averaged PERG waveforms showing P1 and N2 amplitudes (ampl.) in 6- and 12 month old wild type (WT) and Apoj^−/− mice. B The quantifications of the P1 an N2 amplitudes. Data represent the mean ± SD of the measurements in one eye from each animal (6 month old group: 16 female and 11 male WT mice and 20 female and 12 male Apoj^−/− mice; and 12 month old group: 6 female and 7 male WT mice and 5 female and 8 male Apoj^−/− mice). *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001 as assessed by two-way ANOVA with Tukey's multiple comparison test