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. 2023 Jul 1;13:10690. doi: 10.1038/s41598-023-37862-y

Table 1.

Patients’ demographic characteristics.

Overall (n = 55) PD (progressive disease, n = 18) Non-PD (n = 37) P-value
Sex (%) 0.160
 Female 5 (9.1) 0 (0.0) 5 (13.5)
 Male 50 (90.9) 18 (100.0) 32 (86.5)
 Age (median [interquartile range, IQR]) 53.00 [43.00, 55.00] 51.50 [48.50, 55.00] 53.00 [43.00, 57.00] 0.336
Hepatitis B virus infection (%) 0.247
 No 3 (5.5) 2 (11.1) 1 (2.7)
 Yes 52 (94.5) 16 (88.9) 36 (97.3)
 Platelets (median [IQR]) 194.00 [162.50, 282.50] 198.50 [160.50, 319.00] 192.00 [164.00, 281.00] 0.851
 Albumin-bilirubin (mean (standard deviation, SD)) − 2.60 (0.44) − 2.29 (0.38) − 2.76 (0.38)  < 0.001
 Aspartate aminotransferase (median [IQR]) 60.30 [36.90, 95.00] 64.85 [40.17, 116.58] 60.30 [36.90, 84.10] 0.379
 Alanine transaminase (median [IQR]) 44.50 [30.45, 66.30] 48.75 [28.85, 71.20] 40.90 [30.70, 66.00] 0.713
 Alkaline phosphatase (median [IQR]) 134.10 [102.90, 182.50] 137.75 [101.62, 219.65] 131.00 [106.60, 173.60] 0.446
Alpha fetoprotein level (%) 0.761
 < 200 ng/ml 18 (32.7) 5 (27.8) 13 (35.1)
 ≥ 200 ng/ml 37 (67.3) 13 (72.2) 24 (64.9)
Number (%)  > 0.99
 Single 21 (38.2) 7 (38.9) 14 (37.8)
 Multiple 34 (61.8) 11 (61.1) 23 (62.2)
Diameter (%) 0.713
 < 5 cm 10 (18.2) 4 (22.2) 6 (16.2)
 ≥ 5 cm 45 (81.8) 14 (77.8) 31 (83.8)
Vascular invasion (%)  > 0.99
 No 11 (20.0) 3 (16.7) 8 (21.6)
 Yes 44 (80.0) 15 (83.3) 29 (78.4)
Distant spread (%) 0.764
 No 36 (65.5) 11 (61.1) 25 (67.6)
 Yes 19 (34.5) 7 (38.9) 12 (32.4)