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. 2023 Feb 3;9(1-4):100–118. doi: 10.1159/000529536

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Fig. 1. — Study overview. a Flow diagram of the PRISMA study selection workflow in our systematic literature review. The identification and screening process of selected reports, focused on brain-specific transcriptomic and epigenomic studies of PTSD in humans and animal models, is shown. b Cross-species convergence in PTSD. The number of identified transcriptomic and epigenomic studies in animal models and humans is depicted. A high variability is observed in the brain regions examined across species. Subgenual prefrontal cortex (sgPFC), orbitofrontal cortex (OFC), dorsolateral prefrontal cortex (dlPFC), dorsolateral anterior cingulate cortex (dACC), ventromedial prefrontal cortex (vmPFC), amygdala (AMY), hippocampus (Hippo), hemibrain (Hemibr), medial prefrontal cortex (mPFC), ventral striatum (VS), septal region (SE), corpus striatum (ST).