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. 1988 Feb;51(2):218–222. doi: 10.1136/jnnp.51.2.218

"Alien hand" and loss of bimanual coordination after dominant anterior cerebral artery territory infarction.

A W McNabb 1, W M Carroll 1, F L Mastaglia 1
PMCID: PMC1031534  PMID: 3346686

Abstract

Three patients with dominant anterior cerebral artery territory infarction demonstrated a severe disturbance of upper limb motor control with impaired bimanual coordination, the "alien hand" sign, and intermanual conflict, in addition to signs of callosal interruption and a transcortical motor aphasia. Recordings of movement-related potentials in one patient showed an attenuated Bereitschaftspotential and a greater asymmetry of the NS' component of the premotor negativity with left finger than with right finger movement. The impairment of bimanual motor control and associated abnormal motor behaviour of the right hand in these cases are postulated to be due to involvement of the supplementary motor area and related areas of the medial frontal cortex.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alexander M. P., Schmitt M. A. The aphasia syndrome of stroke in the left anterior cerebral artery territory. Arch Neurol. 1980 Feb;37(2):97–100. doi: 10.1001/archneur.1980.00500510055010. [DOI] [PubMed] [Google Scholar]
  2. Barrett G., Shibasaki H., Neshige R. Cortical potentials preceding voluntary movement: evidence for three periods of preparation in man. Electroencephalogr Clin Neurophysiol. 1986 Apr;63(4):327–339. doi: 10.1016/0013-4694(86)90017-9. [DOI] [PubMed] [Google Scholar]
  3. Boschert J., Hink R. F., Deecke L. Finger movement versus toe movement-related potentials: further evidence for supplementary motor area (SMA) participation prior to voluntary action. Exp Brain Res. 1983;52(1):73–80. doi: 10.1007/BF00237151. [DOI] [PubMed] [Google Scholar]
  4. Brinkman C. Lesions in supplementary motor area interfere with a monkey's performance of a bimanual coordination task. Neurosci Lett. 1981 Dec 23;27(3):267–270. doi: 10.1016/0304-3940(81)90441-9. [DOI] [PubMed] [Google Scholar]
  5. Brinkman C., Porter R. Supplementary motor area in the monkey: activity of neurons during performance of a learned motor task. J Neurophysiol. 1979 May;42(3):681–709. doi: 10.1152/jn.1979.42.3.681. [DOI] [PubMed] [Google Scholar]
  6. Brion S., Jedynak C. P. Troubles du transfert interhémisphérique (callosal disconnection). A propos de trois observations de tumeurs du corps calleux. Le signe de la main étrangére. Rev Neurol (Paris) 1972 Apr;126(4):257–266. [PubMed] [Google Scholar]
  7. Deecke L., Grözinger B., Kornhuber H. H. Voluntary finger movement in man: cerebral potentials and theory. Biol Cybern. 1976 Jul 14;23(2):99–119. doi: 10.1007/BF00336013. [DOI] [PubMed] [Google Scholar]
  8. Deecke L., Kornhuber H. H. An electrical sign of participation of the mesial 'supplementary' motor cortex in human voluntary finger movement. Brain Res. 1978 Dec 29;159(2):473–476. doi: 10.1016/0006-8993(78)90561-9. [DOI] [PubMed] [Google Scholar]
  9. Deecke L., Scheid P., Kornhuber H. H. Distribution of readiness potential, pre-motion positivity, and motor potential of the human cerebral cortex preceding voluntary finger movements. Exp Brain Res. 1969;7(2):158–168. doi: 10.1007/BF00235441. [DOI] [PubMed] [Google Scholar]
  10. Dick J. P., Benecke R., Rothwell J. C., Day B. L., Marsden C. D. Simple and complex movements in a patient with infarction of the right supplementary motor area. Mov Disord. 1986;1(4):255–266. doi: 10.1002/mds.870010405. [DOI] [PubMed] [Google Scholar]
  11. Freedman M., Alexander M. P., Naeser M. A. Anatomic basis of transcortical motor aphasia. Neurology. 1984 Apr;34(4):409–417. doi: 10.1212/wnl.34.4.409. [DOI] [PubMed] [Google Scholar]
  12. Geschwind N. Disconnexion syndromes in animals and man. I. Brain. 1965 Jun;88(2):237–294. doi: 10.1093/brain/88.2.237. [DOI] [PubMed] [Google Scholar]
  13. Goldberg G., Mayer N. H., Toglia J. U. Medial frontal cortex infarction and the alien hand sign. Arch Neurol. 1981 Nov;38(11):683–686. doi: 10.1001/archneur.1981.00510110043004. [DOI] [PubMed] [Google Scholar]
  14. Laplane D., Talairach J., Meininger V., Bancaud J., Orgogozo J. M. Clinical consequences of corticectomies involving the supplementary motor area in man. J Neurol Sci. 1977 Dec;34(3):301–314. doi: 10.1016/0022-510x(77)90148-4. [DOI] [PubMed] [Google Scholar]
  15. Lee B. I., Lüders H., Lesser R. P., Dinner D. S., Morris H. H., 3rd Cortical potentials related to voluntary and passive finger movements recorded from subdural electrodes in humans. Ann Neurol. 1986 Jul;20(1):32–37. doi: 10.1002/ana.410200107. [DOI] [PubMed] [Google Scholar]
  16. Roland P. E., Larsen B., Lassen N. A., Skinhøj E. Supplementary motor area and other cortical areas in organization of voluntary movements in man. J Neurophysiol. 1980 Jan;43(1):118–136. doi: 10.1152/jn.1980.43.1.118. [DOI] [PubMed] [Google Scholar]
  17. Ross E. D. Left medial parietal lobe and receptive language functions: mixed transcortical aphasia after left anterior cerebral artery infarction. Neurology. 1980 Feb;30(2):144–151. doi: 10.1212/wnl.30.2.144. [DOI] [PubMed] [Google Scholar]
  18. Shibasaki H., Barrett G., Halliday E., Halliday A. M. Components of the movement-related cortical potential and their scalp topography. Electroencephalogr Clin Neurophysiol. 1980 Aug;49(3-4):213–226. doi: 10.1016/0013-4694(80)90216-3. [DOI] [PubMed] [Google Scholar]
  19. Talairach J., Bancaud J., Geier S., Bordas-Ferrer M., Bonis A., Szikla G., Rusu M. The cingulate gyrus and human behaviour. Electroencephalogr Clin Neurophysiol. 1973 Jan;34(1):45–52. doi: 10.1016/0013-4694(73)90149-1. [DOI] [PubMed] [Google Scholar]
  20. Tamas L. B., Shibasaki H. Cortical potentials associated with movement: a review. J Clin Neurophysiol. 1985 Apr;2(2):157–171. doi: 10.1097/00004691-198504000-00003. [DOI] [PubMed] [Google Scholar]
  21. Thickbroom G. W., Mastaglia F. L., Carroll W. M., Davies H. D. Cerebral potentials accompanying visually triggered finger movement in man. Electroencephalogr Clin Neurophysiol. 1985 May;62(3):209–218. doi: 10.1016/0168-5597(85)90016-4. [DOI] [PubMed] [Google Scholar]
  22. Watson R. T., Heilman K. M. Callosal apraxia. Brain. 1983 Jun;106(Pt 2):391–403. doi: 10.1093/brain/106.2.391. [DOI] [PubMed] [Google Scholar]

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