Fig. 8.

Light-triggered release of nintedanib (BIBF) post-injection inhibits CNV. A Fluorescent microscope images of isolectin B4-Alexa Fluor 594 stained choroidal flat-mounts 2 weeks after CNV induction. The eyes were irradiated immediately post-injection (scale bar = 100 µm). B Quantification of CNV spot size (n = 4–6). C Choroidal flat-mounts from the eyes irradiated 10 weeks post-injection, 2 weeks after CNV induction (scale bar = 100 µm). D Quantification of CNV spot size (n = 4–6). Copyright 2015, Elsevier. Reproduced from [82] with permission