Table III. Variables tested to probe heterogeneity of immunological vaccine responses.
| Variable | Hazard Ratio | 95% CI | p Value |
|---|---|---|---|
| E75 Tetramer | 0.93 | 0.81–1.07 | 0.32 |
| E75 CD107 | 1.01 | 0.97–1.05 | 0.55 |
| E75 IFNg | 1.00 | 0.87–1.16 | 0.99 |
| E90 tetramer | 1.03 | 0.92–1.15 | 0.59 |
| E90 CD107 | 1.02 | 0.99–1.05 | 0.25 |
| E90 IFNg | 1.02 | 0.95–1.10 | 0.61 |
Assessment of vaccine responses was based on number of epitope-specific CD8+ T cells, IFN-γ secretion, cell-surface CD107a expression as determined by flow cytometric analysis. None of the variables tested were significantly associated with OS postvaccination.