Figure 4:

Images in a 74-year-old man with a serum prostate-specific antigen level of 12.9 ng/mL. (A) Axial T2-weighted MRI scan, (B) apparent diffusion coefficient map, and (C) diffusion-weighted image with a b value of 1500 sec/mm² demonstrate no focal lesion within the prostate gland. (D) Dynamic contrast-enhanced MRI scan shows a very subtle linear enhancement in the right mid peripheral zone (arrow). Overall, the multiparametric MRI examination was negative for a cancer-suspicious lesion according to the Prostate Imaging Reporting and Data System. (E) Axial fluorine 18 DCFPyL PET/CT image demonstrates bilateral uptake (greater on the right side) in the prostate (arrows). Prostate biopsy revealed Gleason 4+3 prostate cancer within the right mid peripheral zone. DCFPyL = 2-(3-{1-carboxy-5-[(6-¹⁸F-fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid).