Reviewer name and names of any other individual's who aided in reviewer	Nazila Godfrey
Do you understand and agree to our policy of having open and named reviews, and having your review included with the published papers. (If no, please inform the editor that you cannot review this manuscript.)	Yes
Is the language of sufficient quality?	No
Please add additional comments on language quality to clarify if needed	The writing needs to be improved significantly.
Are all data available and do they match the descriptions in the paper?	No
Additional Comments	There is only one Biosample submitted for this project while in methods is mentioned samples. It is not clear if the biosample is for DNA or RNA. Following sequencing data depends on this too.
Are the data and metadata consistent with relevant minimum information or reporting standards? See GigaDB checklists for examples <a href="http://gigadb.org/site/guide" target="_blank">http://gigadb.org/site/guide</a>	No
Additional Comments	Fasta files required for genome assembly and BUSCO files are missing.
Is the data acquisition clear, complete and methodologically sound?	No
Additional Comments	The genome assemblies that are used need to be properly cited.
Is there sufficient detail in the methods and data-processing steps to allow reproduction?	No
Additional Comments
Is there sufficient data validation and statistical analyses of data quality?	No
Additional Comments
Is the validation suitable for this type of data?	Yes
Additional Comments
Is there sufficient information for others to reuse this dataset or integrate it with other data?	No
Additional Comments
Any Additional Overall Comments to the Author	Introduction needs to be elaborated heavily. The importance of study needs to be clarified. Why only %6 of the bite cases is treated with antivenom? Is that because bites usually happen in remote areas, or we don’t have antivenom? It is confusing. Why genome sequencing is necessary for designing an antivenom? Main content section needs to be expanded and elaborated. It is not clear why at the end of this section they made such a statement: “This suggests that the significant expansion of repeating elements is an important manifestation of species differences”. Explain in the text.
Recommendation	Major Revision