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. 2023 May 17;12:105–111. doi: 10.1016/j.jdin.2023.05.001

Table II.

Summary of the clinical presentation, histology and tuberculin skin test for the subtypes of cutaneous tuberculosis

Form of CTB Clinical presentation Histology and TST
Lupus vulgaris Nontender plaques or nodules with ulceration
Progress to well-defined, scaly plaques
Located on face or neck (hematogenous spread) or extremities (exogenous reinoculation)
Cervical and supraclavicular lymphadenopathy
Paucibacillary
Granulomas, giant cells, and caseous necrosis
Positive TST
Tuberculous chancre Erythematous papules
Progress to firm non-tender ulcers
Upper and lower limbs
+/− Lymphadenopathy
Multibacillary
Granulomatous inflammation with caseous necrosis
TST is positive.
Tuberculosis verrucose cutis Small papules surrounded by inflammation that develops into a wart-like lesion Paucibacillary
Hyperkeratosis and tuberculoid granulomas in the dermis
Positive TST
Periorificial lesions Painful ulcers in the oral or perineal regions Multibacillary
Granulomatous inflammation with caseous necrosis
Scrofuloderma Firm nodules which ulcerate, forming purulent sinus tracts
Cervical and postauricular lymphadenopathy
Multibacillary
Granulomatous inflammation with caseous necrosis
Tuberculosis miliaris cutis disseminate Widespread papules and crusted vesicles
Immunocompromised patient
Multibacillary
Nonspecific inflammation with necrotizing vasculitis
Metastatic abscesses Multiple nodules that may ulcerate or form draining sinus tracts
+/− Cervical lymphadenopathy
Multibacillary
Granulomatous inflammation with caseous necrosis
Tuberculid forms
Lichen Scrofulosorum
Papulonecrotic Tuberculid
Lichenoid papules which may form plaques and scale
Bilateral and symmetrical distribution
Necrotic papules
Paucibacillary; TST positive
Granulomatous inflammation without caseation with a parakeratotic epidermis
Necrosis and granulomatous inflammation