Table II.
Form of CTB | Clinical presentation | Histology and TST |
---|---|---|
Lupus vulgaris | Nontender plaques or nodules with ulceration Progress to well-defined, scaly plaques Located on face or neck (hematogenous spread) or extremities (exogenous reinoculation) Cervical and supraclavicular lymphadenopathy |
Paucibacillary Granulomas, giant cells, and caseous necrosis Positive TST |
Tuberculous chancre | Erythematous papules Progress to firm non-tender ulcers Upper and lower limbs +/− Lymphadenopathy |
Multibacillary Granulomatous inflammation with caseous necrosis TST is positive. |
Tuberculosis verrucose cutis | Small papules surrounded by inflammation that develops into a wart-like lesion | Paucibacillary Hyperkeratosis and tuberculoid granulomas in the dermis Positive TST |
Periorificial lesions | Painful ulcers in the oral or perineal regions | Multibacillary Granulomatous inflammation with caseous necrosis |
Scrofuloderma | Firm nodules which ulcerate, forming purulent sinus tracts Cervical and postauricular lymphadenopathy |
Multibacillary Granulomatous inflammation with caseous necrosis |
Tuberculosis miliaris cutis disseminate | Widespread papules and crusted vesicles Immunocompromised patient |
Multibacillary Nonspecific inflammation with necrotizing vasculitis |
Metastatic abscesses | Multiple nodules that may ulcerate or form draining sinus tracts +/− Cervical lymphadenopathy |
Multibacillary Granulomatous inflammation with caseous necrosis |
Tuberculid forms Lichen Scrofulosorum Papulonecrotic Tuberculid |
Lichenoid papules which may form plaques and scale Bilateral and symmetrical distribution Necrotic papules |
Paucibacillary; TST positive Granulomatous inflammation without caseation with a parakeratotic epidermis Necrosis and granulomatous inflammation |