TABLE 3.
Multivariable logistic analysis of factors influencing the efficacy of neoadjuvant chemotherapy.
| Factors | TRG | RECIST1.1 | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p | OR | 95% CI | p | |
| Sex | ||||||
| Female | Reference | — | ||||
| Male | 0.464 | 0.162–1.193 | 0.126 | — | ||
| Differentiation (before NACT) | ||||||
| Poorly | Reference | Reference | ||||
| Moderate and well | 4.276 | 1.851–10.974 | 0.001 | 4.850 | 2.103–12.479 | <0.001 |
| cT stage | ||||||
| 2 | Reference | Reference | ||||
| 3 | 0.372 | 0.082–1.447 | 0.170 | 0.645 | 0.147–2.450 | 0.534 |
| 4 | 0.135 | 0.024–0.678 | 0.018 | 0.155 | 0.028–0.758 | 0.025 |
| Tumor diameter | ||||||
| <5 cm | Reference | Reference | ||||
| ≥5 cm | 0.342 | 0.171–0.670 | 0.002 | 0.412 | 0.208–0.805 | 0.010 |
| Chemotherapy cycles | ||||||
| 2–3 | Reference | — | ||||
| 4 | 2.158 | 1.084–4.419 | 0.031 | — | ||
| cTNM | ||||||
| III | Reference | Reference | ||||
| IIa | 0.644 | 0.224–1.837 | 0.409 | 1.067 | 0.377–3.088 | 0.903 |
| IIb | 0.739 | 0.309–1.728 | 0.488 | 0.706 | 0.299–1.621 | 0.418 |