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. 2023 May 29;27(13):1836–1858. doi: 10.1111/jcmm.17782

FIGURE 6.

FIGURE 6

Hypoxic preconditioned bone marrow‐derived mesenchymal stem cells (HP‐BMSCs) reduced the expression of pyroptosis‐related molecules in the cortex after resuscitation. (A) Western blotting results showing expression of NLRP3, cleaved‐caspase‐1, GSDMD‐N and ASC in post‐resuscitation rats (n = 3). (B–E) Quantitative analysis of target proteins. (F, G) Expression level of IL‐1β and IL‐18 in the cortex after ROSC in the indicated groups (n = 5–6). All data are presented as the means ± SD. *p < 0.05 vs. the sham group. # p < 0.05 vs. the CPR + PBS group. & p < 0.05 vs. the CPR + normal‐cultured BMSCs (N‐BMSCs) group.