Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 19;10:1208275. doi: 10.3389/fvets.2023.1208275

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Zajac, Trujillo, Yao, Kumar, Sangewar, Lokhandwala, Sang, Mallen, McCall, Burton, Kumar, Heitmann, Burnum, Waghela, Almes, Richt, Kim and Mwangi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Study design and timeline. (A) Pigs were randomly assigned to four treatment groups: (1) Ad5-Luciferase plus Montanide ISA-201™ adjuvant (Luc-ISA-201); (2) Ad5-ASFV cocktail (ASFV-No Adjuvant); (3) Ad5-ASFV cocktail plus Montanide ISA-201™ adjuvant (ASFV-ISA-201); or (4) Ad5-ASFV cocktail plus BioMize^® adjuvant (ASFV-BioMize). (B) Animals were acclimatized for 1 week and baseline serum and PBMC samples were collected with weekly collections thereafter. Pigs in all the treatment groups were primed after acclimatization followed by boosting at weeks 3 and 7 post-priming as shown in Table 2. The pigs were challenged by contact with comingled ASFV-infected naïve pigs at week 9. Blood and nasal swabs were collected until termination. The survivor from the ASFV-No Adjuvant group was terminated 37 days post-challenge. Created with BioRender.com (accessed on 17 April 2023).