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. 2022 Dec 15;108(7):1909–1919. doi: 10.3324/haematol.2022.280993

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Figure 2. — RUNX1 deletions. (A) RUNX1 deletions identified by exome sequencing were confirmed by chromosomal microarray analysis. Profiles from probands of Families 44, 66 and 72 (top to bottom panels) are shown. Highlighting indicates deleted regions. The top panel was produced by the UCSC Genome Browser (https://genome.ucsc.edu/) and shows the genomic positions and all genes included in the region. Segregation of deletions was evaluated by real-time polymerase chain reaction in Family.44 (B), Family.66 (C) and Family.72 (D). Genotype is reported when available.