Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 29;108(7):1861–1872. doi: 10.3324/haematol.2022.281505

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright© 2023 Ferrata Storti Foundation

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PMC Copyright notice

Figure 5. — Localization of targeted nanobubbles on endothelium and vascular thrombi during thrombolytic treatment in a rat model of antiphospolipid syndrome. Thrombus formation and nanobubble (NB) deposits were followed by intravital microscopy and the images were collected 90 minutes after injection of NB. Residual intravascular thrombi are visualized in red by in vivo staining with rhodamine 6G and NB loaded with coumarin 6 in green. Arrows show the co-localization of rtPA-tNB and residual vascular thrombi and arrowheads highlight the localization of rtPA-tNB on activated endothelium. Note the absence of untargeted NB and the presence of occluded vessels in rtPA-NB-treated animal. TNB: targeted NB; rtPA: recombinant tissue plasminogen activator.