Figure 4.

Detection of SARS-CoV-2-reactive T cells before and afer infusion in the four infused patients. Specific cells are measured by ELIspot using the five targeted antigens as a stimulus. Results are reported as spot-forming cells ± standard error of mean and each color represents an individual antigenic specificity. In addition, the red arrows indicate each time point at which T-cell receptor deep sequencing confirmed the presence of infused virus-specific T cells in the patients. SFC: spot-forming cells; D1: day 1; Wk: week; Mo: month; N: nucleocapsid; M: membrane; S: spike; TCR: T-cell receptor.