Table 4.
Molecules and pathways involved in autophagy in TMJ OA.
| Main Factors | Pathways | Effect on Autophagy | References |
|---|---|---|---|
| Mettl3 | m6A/Ythdf1/Bcl2 | Inhibition | 70 |
| mTOR | – | Inhibition | 71 |
| mTOR, estrogen | – | Inhibition | 72 |
| mTORC1 | – | Inhibition | 67 |
| FGFR1 | – | Inhibition | 73 |
Abbreviations: mettl3: m6A regulators like methyltransferase-like 3; Ythdf1: YT521-B homology (YTH) domain-containing proteins 1; m6A: N6-methyladenosine; mTOR: mammalian target of rapamycin; mTORC: mammalian target of rapamycin complex; FGFR1: fibroblast growth factor receptor type 1.