Table 3.
Univariate and multivariate analysis of factors associated with progression‐free survival.
| Characteristic | HR. (95% CI) | Univariate analysis p-value |
HR. (95% CI) | Multivariate analysis p-value |
|---|---|---|---|---|
| Age group (<40 vs. ≥40) | 0.433 (0.224-0.839) | 0.013 | 0.528 (0.238-1.174) | 0.117 |
| ECOG performance status (0-1 vs ≥2) | 0.419 (0.162-1.088) | 0.074 | 0.440 (0.150-1.295) | 0.136 |
| Menstrual status (pre vs. post) | 0.454 (0.230-0.896) | 0.023 | 1.156 (0.468-2.860) | 0.753 |
| Hormone receptor status (negative vs. positive) | 1.982 (1.064-3.692) | 0.031 | 1.426 (0.704-2.885) | 0.324 |
| DFI (≤12 months vs.>12 months vs. de novo IV stage) | 1.375 (0.564-3.353) | 0.484 | N/A* | N/A |
| Number of sites in primary recurrence (1 vs. >1) | 1.350 (0.729-2.498) | 0.340 | N/A | N/A |
| Number of metastatic sites before inetetamab (1 vs. ≥2) | 0.838 (0.447-1.573) | 0.583 | N/A | N/A |
| Brain metastasis (no vs. yes) | 1.516 (0.731-3.145) | 0.263 | N/A | N/A |
| Visceral metastasis (no vs. yes) | 1.735 (0.928-3.244) | 0.084 | 2.444 (1.095-5.457) | 0.029 |
| Regimens (other therapeutic agents vs. inetetamab + vinorelbine + pyrotinib) | 2.167 (1.140-4.119) | 0.018 | 3.543 (1.680-7.471) | 0.001 |
*N/A, Not applicable.