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. 2023 Jun 19;13:1136380. doi: 10.3389/fonc.2023.1136380

Table 3.

Univariate and multivariate analysis of factors associated with progression‐free survival.

Characteristic HR. (95% CI) Univariate analysis
p-value
HR. (95% CI) Multivariate analysis
p-value
Age group (<40 vs. ≥40) 0.433 (0.224-0.839) 0.013 0.528 (0.238-1.174) 0.117
ECOG performance status (0-1 vs ≥2) 0.419 (0.162-1.088) 0.074 0.440 (0.150-1.295) 0.136
Menstrual status (pre vs. post) 0.454 (0.230-0.896) 0.023 1.156 (0.468-2.860) 0.753
Hormone receptor status (negative vs. positive) 1.982 (1.064-3.692) 0.031 1.426 (0.704-2.885) 0.324
DFI (≤12 months vs.>12 months vs. de novo IV stage) 1.375 (0.564-3.353) 0.484 N/A* N/A
Number of sites in primary recurrence (1 vs. >1) 1.350 (0.729-2.498) 0.340 N/A N/A
Number of metastatic sites before inetetamab (1 vs. ≥2) 0.838 (0.447-1.573) 0.583 N/A N/A
Brain metastasis (no vs. yes) 1.516 (0.731-3.145) 0.263 N/A N/A
Visceral metastasis (no vs. yes) 1.735 (0.928-3.244) 0.084 2.444 (1.095-5.457) 0.029
Regimens (other therapeutic agents vs. inetetamab + vinorelbine + pyrotinib) 2.167 (1.140-4.119) 0.018 3.543 (1.680-7.471) 0.001

*N/A, Not applicable.