Figure 2.
Resting-state SEEG connectivity. (A) Undirected alpha-band ImCoh was elevated for SOZs and PZs (one-way ANOVA P = 2.13 × 10−3 with post hoc multiple pairwise t-test comparisons significant for SOZ-NIZ and PZ-NIZ. (B) Inwards PDC strength was elevated significantly for SOZs and PZs (one-way ANOVA P = 1.75 × 10−12 with post hoc multiple pairwise t-test comparisons significant between all three groups. (C) Outwards PDC strength was significantly lower for SOZs and PZs (one-way ANOVA P = 4.95 × 10−10 with post hoc multiple pairwise t-test comparisons significant between all three groups. (D) Inwards—outwards (reciprocal) connectivity exhibited a stronger signal to that of inwards or outwards separately (one-way ANOVA P = 3.13 × 10−13 with post hoc multiple pairwise t-test comparisons significant between all three groups). Box represents first quartile, mean and third quartile. Whiskers represent maximum and minimum. *P < 5 × 10−2, **P < 5 × 10−3, ***P < 5 × 10−6. n = 81 subjects.