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. 2019 Dec;41(12):710–717. doi: 10.1055/s-0039-3400457

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Fig. 2 — Receiver operating characteristic (ROC) curve analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki67 expression as predictors of clinical complete response (cCR). (A) ER expression. The calculated area under the curve (AUC) was of 0.619 (95% confidence interval [95%CI]: 0.516–0.722; p = 0.03); a cut-off point of 85% had a sensitivity of 77.5% and a specificity of 43.8% to identify patients who are likely to develop cCR. (B) PR expression. The AUC was of 0.623 (95%CI: 0.518–0.728; p = 0.026); a cut-off point of 50% had a sensitivity of 73.5% and a specificity of 48.4%. (C) Ki67 expression. The AUC was of 0.642 (95%CI: 0.536–0.747; p = 0.013); a cut-off point of 14% had a sensitivity of 86.1% and a specificity of 39.1%.